Facilities and Maintenance Engineering Technician

The Facilities & Maintenance Technician is responsible for executing MeiraGTx's maintenance, calibration, utilities and facilities activities to ensure the operational readiness and availability of assets across the UK site. The role delivers a high-quality and auditable standard for planned and unplanned maintenance while supporting the reliability, lifecycle optimisation, and safe operation of equipment, utilities and GMP-critical systems.

Major Activities and Responsibilities

GMP Calibration & Maintenance

• Execute internal and host external planned preventative maintenance (PPM), calibration and reactive maintenance activities to the required Engineering, EHS, and GMP standards.
• Ensure adherence to maintenance procedures and accurate interaction with the CMMS during task execution.
• Ensure availability and reliability of building utilities, facility services and manufacturing equipment.

Critical Spares & Asset Management

• Support maintenance of critical spares stocklist and Maximo asset records, ensuring correct stock levels and traceability.

Contractor & Vendor Management

• Oversee service contractor activities for PPM/reactive tasks, including EHS permitting and compliance with site procedures.
• Maintain effective working relationships with onsite vendors and third‑party specialists.

Facilities Management

• Support and oversee GMP‑related facilities management activities, ensuring building, utility and environmental systems remain audit‑ready.

Project Engineering & Management

• Execute assigned project tasks in a timely manner with good documentation practices (GDP).

Process & Technical Engineering

• Assist with technical troubleshooting using Good Engineering Practice to resolve equipment/process issues.

Safety Culture & Safety Processes

• Follow Machinery Safety, Electrical Safety and Permit‑to‑Work processes to ensure safe execution of Engineering tasks.
• Partner with EHS to maintain a strong safety culture and deliver all safety commitments on time and in full.

Quality Culture & Inspection Readiness

• Contribute to a robust quality culture to remain audit‑ready at all times.
• Follow all quality processes including CAPA, documentation and procedure improvements.
• Ensure timely, right‑first‑time completion of all assigned GMP documentation.

GDP & GMP Responsibilities

• Ensure work complies with GMP, Data Integrity and Good Documentation Practice.
• Ensure required training is completed prior to performing GMP tasks.

Communication, Teamwork & Continuous Improvement

• Communicate effectively and in a timely manner with all relevant stakeholders.
• Maintain strong cross‑functional relationships to optimise performance.
• Identify and contribute to continuous improvement opportunities.
  

Key Job Competencies

• Possessing or studying towards a recognised Engineering Qualification (HNC, HND, BEng or MEng) or equivalent/suitable previous work experience.
• Responsible for ensuring that own training is undertaken in a timely and GMP compliant manner before the task is undertaken.
• Ability to develop competency with Maintenance, Calibration, Utilities, Facilities, and Asset Management.

MeiraGTx is a clinical-stage gene therapy company focused on developing potentially curative treatments for patients living with serious diseases. We currently have six programs in clinical development including three ocular indications, a salivary gland condition, and a Parkinson’s disease program. Our initial focus on diseases of the eye, salivary gland and central nervous system is based on the significant unmet medical need coupled with the high potential gene therapy has to provide meaningful clinical benefit in these areas. With headquarters in New York and London, our global footprint provides us the opportunity to partner with leading institutions around the world, allowing us to deepen our understanding of diseases and their progression.

Our team was built with deep expertise in gene therapy development, allowing us to efficiently advance our programs from preclinical to clinical development. Our core capabilities in viral vector design and optimization and gene therapy manufacturing give us a differentiated approach to developing gene therapies. Additionally, we are developing proprietary technology to potentially enable innovative gene therapy treatments whose expression can be turned on and off with an easily administered small molecule. We believe temporal control of gene therapy products has the potential to transform the gene therapy landscape.

Our state-of-the-art manufacturing facility, completed in early 2018, was designed to meet global regulatory requirements, including the current good manufacturing practices (cGMP) required by the Medicines and Healthcare products Regulatory Agency (MHRA) in the UK and the U.S. Food and Drug Administration (FDA). The 29,000-square foot facility has the flexibility and capacity to produce sufficient product for all our clinical trials and will scale to commercial capacity.